Article
Introduction of gluten, HLA status, and the risk of celiac disease in children.
The New England journal of medicine - 2 Oct 2014
Lionetti Elena, Castellaneta Stefania, Francavilla Ruggiero, Pulvirenti Alfredo, Tonutti Elio, Amarri Sergio, Barbato Maria, Barbera Cristiana, Barera Graziano, Bellantoni Antonella, Castellano Emanuela, Guariso Graziella, Limongelli Maria Giovanna, Pellegrino Salvatore, Polloni Carlo, Ughi Claudio, Zuin Giovanna, Fasano Alessio, Catassi Carlo
Abstract excerpt
BACKGROUND: The relationship between the risk of celiac disease and both the age at which gluten is introduced to a child's diet and a child's early dietary pattern is unclear. METHODS: We randomly assigned 832 newborns who had a first-degree relative with celiac disease to the introduction of dietary gluten at 6 months (group A) or 12 months (group B). The HLA genotype was determined at 15 months of age, and...
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