Article
Association of a single nucleotide polymorphism in the matrix metalloproteinase-1 promoter with glioblastoma.
International journal of cancer - 10 Dec 2005
McCready Jessica, Broaddus William C, Sykes Virginia, Fillmore Helen L
Abstract excerpt
A key feature in the malignant behavior of glioblastoma is the tendency to invade host brain tissue surrounding the primary tumor site. Several members of the matrix metalloproteinase family are thought to contribute to this invasive capacity. A single nucleotide polymorphism has been described in the matrix metalloproteinase-1 (MMP-1) promoter that consists of either the presence or absence of a guanine...
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