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Article

Shared intermediate phenotypes for schizophrenia and bipolar disorder: neuroanatomical features of subtypes distinguished by executive dysfunction.

Journal of psychiatry & neuroscience : JPN - 1 Jan 2015

Shepherd Alana M, Quidé Yann, Laurens Kristin R, O'Reilly Nicole, Rowland Jesseca E, Mitchell Philip B, Carr Vaughan J, Green Melissa J

Abstract excerpt

BACKGROUND: Shared genetic vulnerability for schizophrenia and bipolar disorder may be associated with common neuroanatomical features. In view of the evidence for working memory dysfunction as a candidate intermediate phenotype for both disorders, we explored neuroanatomical distinctions between subtypes defined according to working memory (n-back task) performance. METHODS: We analyzed T1-weighted MRI scans for...

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Identifiers

PMID: 25268788
DOI: 10.1503/jpn.130283
PMCID: PMC4275333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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