Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia.

doi:10.1016/j.schres.2008.02.014

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia.

Schizophrenia research - 1 Aug 2008

Horan William P, Braff David L, Nuechterlein Keith H, Sugar Catherine A, Cadenhead Kristin S, Calkins Monica E, Dobie Dorcas J, Freedman Robert, Greenwood Tiffany A, Gur Raquel E, Gur Ruben C, Light Gregory A, Mintz James, Olincy Ann, Radant Allan D, Schork Nicholas J, Seidman Larry J, Siever Larry J, Silverman Jeremy M, Stone William S, Swerdlow Neal R, Tsuang Debbie W, Tsuang Ming T, Turetsky Bruce I, Green Michael F

Abstract excerpt

Working memory (WM) impairment is a promising candidate endophenotype for schizophrenia that could facilitate the identification of susceptibility genes for this disorder. The validity of this putative endophenotype was assessed by determining whether 149 probands with schizophrenia and 337 of their first-degree relatives demonstrated WM impairment as compared to 190 unaffected community comparison subjects....

Topics

Adult
Cognition Disorders
Female
Genetic Predisposition to Disease
Humans
Male
Memory, Short-Term
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuropsychological Tests

Phenotype

Psychometrics

Reference Values

Schizophrenia

Serial Learning

Verbal Learning

Source

Open in PubMed Open full text

Identifiers

PMID: 18406578
DOI: 10.1016/j.schres.2008.02.014
PMCID: PMC2529172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.