Article
Influence of APOE-2 genotype on the relation between adiposity and plasma lipid levels in patients with vascular disease.
International journal of obesity (2005) - 1 Feb 2015
Koopal C, van der Graaf Y, Asselbergs F W, Westerink J, Visseren F L J
Abstract excerpt
BACKGROUND: Apolipoprotein E (APOE) genotypes are associated with different plasma lipid levels. People with the APO ɛ2 genotype can develop a disorder called dysbetalipoproteinemia (DBL). A possible predisposing factor for DBL is adiposity. We evaluated whether and to what extent the APOE genotype modifies the relation between adiposity and lipids in patients with manifest arterial disease and we looked at...
Topics
- Adiposity
- Apolipoprotein E2
- Body Fat Distribution
- Body Mass Index
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hyperlipoproteinemia Type III
- Lipids
- Male
- Metabolic Syndrome
- Middle Aged
- Obesity, Abdominal
- Prospective Studies
- Vascular Diseases