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Article

Apolipoprotein E4 association with metabolic syndrome depends on body fatness.

Atherosclerosis - 1 Feb 2016

Torres-Perez Elena, Ledesma Marta, Garcia-Sobreviela Maria Pilar, Leon-Latre Montserrat, Arbones-Mainar Jose M

Abstract excerpt

BACKGROUND AND AIMS: The human Apolipoprotein E (APOE) gene is polymorphic. The APOE*4 allele is a risk factor for cardiovascular disease and could contribute to the development of the metabolic syndrome (MetS) as it may affect all MetS components. We hypothesize that the common APOE4 polymorphism differentially regulates MetS risk and that this association might be modulated by body fatness. METHODS & RESULTS:...

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Source

Identifiers

PMID: 26691908
DOI: 10.1016/j.atherosclerosis.2015.11.029

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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