Article
Association evidence of CCTTT repeat polymorphism in the iNOS promoter and the risk of atrial fibrillation in Taiwanese.
Scientific reports - 13 Feb 2017
Hsu Lung-An, Yeh Yung-Hsin, Chen Wei-Jan, Kuo Chi-Tai, Tsai Feng-Chun, Chan Yi-Hsin, Wang Chun-Li, Chang Chi-Jen, Tsai Hsin-Yi
Abstract excerpt
Inducible nitric oxide synthase (iNOS) plays an important role in the pathogenesis of atrial fibrillation (AF). The iNOS promoter has a CCTTT-repeat length polymorphism that can determine the level of gene transcription. This study enrolled 200 AF patients and 240 controls. The length of CCTTT-repeat polymorphism in the iNOS promoter region was examined by polymerase chain reactions, with the alleles with ≤11...
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