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Article

STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer

29 Sept 2014

Abstract excerpt

Recent studies of the interferon-induced transcription factor STAT1 have associated its dysregulation with poor prognosis in some cancers, but its mechanistic contributions are not well defined. In this study, we report that the STAT1 pathway is constitutively upregulated in type II endometrial cancers. STAT1 pathway alteration was especially prominent in serous papillary endometrial cancers (SPEC) that are...

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PMID: 25267067
DOI: 10.1158/0008-5472.can-14-0847

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