Article
Detection and comparison of EGFR mutations from supernatants that contain cell-free DNA and cell pellets from FNA non-small cell lung cancer specimens.
Cancer cytopathology - 1 Aug 2020
Wu Wei, Huang Yan, Guo Junhong, Xie Xiaofeng, Li Hui, Cao Ziyang, Wei Haiting, Wu Chunyan
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) is an important marker for targeted therapy in patients with advanced non-small cell lung cancer (NSCLC). The samples obtained with minimally invasive biopsy techniques are usually small, and this limits their application in tissue subtyping or molecular profiling. The supernatants obtained after centrifugation of fine-needle aspiration (FNA) samples are...
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