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Article

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas.

Oncotarget - 30 Sept 2014

Cryan Jane B, Haidar Sam, Ramkissoon Lori A, Bi Wenya Linda, Knoff David S, Schultz Nikolaus, Abedalthagafi Malak, Brown Loreal, Wen Patrick Y, Reardon David A, Dunn Ian F, Folkerth Rebecca D, Santagata Sandro, Lindeman Neal I, Ligon Azra H, Beroukhim Rameen, Hornick Jason L, Alexander Brian M, Ligon Keith L, Ramkissoon Shakti H

Abstract excerpt

Classifying adult gliomas remains largely a histologic diagnosis based on morphology; however astrocytic, oligodendroglial and mixed lineage tumors can display overlapping histologic features. We used multiplexed exome sequencing (OncoPanel) on 108 primary or recurrent adult gliomas, comprising 6...

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Identifiers

PMID: 25257301
DOI: 10.18632/oncotarget.2342
PMCID: PMC4226668

Genes

ATRX
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25257301-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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