Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alcohol Consumption During Gestation Causes Histone3 Lysine9 Hyperacetylation and an Alternation of Expression of Heart Development‐Related Genes in Mice

1 Sept 2014

Abstract excerpt

BACKGROUND: Alcohol abuse during gestation may cause congenital heart diseases (CHDs). The underlying mechanisms of alcohol-induced cardiac deformities are still not clear. Recent studies suggest that histone modification may play a crucial role in this pathological process. Moreover, our previous studies reported that ethanol could induce histone3 lysine9 (H3K9) hyperacetylation and overexpression of heart...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Consumption and Health Effects
Share to Congenital heart defects research
Share to Prenatal Substance Exposure Effects

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25257289
DOI: 10.1111/acer.12518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alcohol Consumption During Gestation Causes Histone3 Lysine9 Hyperacetylation and an Alternation of Expression of Heart Development‐Related Genes in MicePMID 25257289Read ↗

Prenatal alcohol exposure induced congenital heart diseases: From bench to bedsideSemantic proximity Read ↗

Ethanol-induced activation of BMP signaling and reprogramming of cardiomyocytes transcriptomeSemantic proximity Read ↗

Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the HeartSemantic proximity Read ↗

In Utero Alcohol Exposure and the Alteration of Histone Marks in the Developing Fetus: An Epigenetic Phenomenon of Maternal DrinkingSemantic proximity Read ↗

Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse modelSemantic proximity Read ↗

Diet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal MuscleSemantic proximity Read ↗

Role of DNA methylation in perinatal nicotine-induced development of heart ischemia-sensitive phenotype in rat offspringSemantic proximity Read ↗

Embryonic Ethanol Exposure Affects Early- and Late-Added Cardiac Precursors and Produces Long-Lasting Heart Chamber Defects in ZebrafishSemantic proximity Read ↗

miR-153-3p Targets βII Spectrin to Regulate Formaldehyde-Induced Cardiomyocyte ApoptosisSemantic proximity Read ↗

Chronic Prenatal Hypoxia Induces Epigenetic Programming of PKCε Gene Repression in Rat HeartsSemantic proximity Read ↗

Uteroplacental insufficiency induces site-specific changes in histone H3 covalent modifications and affects DNA-histone H3 positioning in day 0 IUGR rat liver.Semantic proximity Read ↗

Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.