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Article

Uteroplacental insufficiency induces site-specific changes in histone H3 covalent modifications and affects DNA-histone H3 positioning in day 0 IUGR rat liver.

Physiological genomics - 15 Dec 2004

Fu Qi, McKnight Robert A, Yu Xing, Wang Laiyi, Callaway Christopher W, Lane Robert H

Abstract excerpt

Uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) increase the risk of adult onset insulin resistance and dyslipidemia in humans and rats. IUGR rats are further characterized by postnatal alterations in hepatic PPAR-gamma coactivator (PGC-1) and carnitine-palmitoyl-transferase I (CPTI) expression, as well as overall hyperacetylation of histone H3. However, it is unknown whether...

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Source

Identifiers

PMID: 15494474
DOI: 10.1152/physiolgenomics.00175.2004

Genes

PGC
HDAC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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