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Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model

15 May 2018

Abstract excerpt

Prenatal alcohol exposure (PAE) can harm the embryonic development and cause life-long consequences in offspring's health. To clarify the molecular mechanisms of PAE we have used a mouse model of early alcohol exposure, which is based on maternal ad libitum ingestion of 10% (v/v) ethanol for the first eight days of gestation (GD 0.5-8.5). Owing to the detected postnatal growth-restricted phenotype in the...

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Share to Epigenetics and DNA Methylation
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PMID: 29763474
DOI: 10.1371/journal.pone.0197461

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