Article
Analysis of two susceptibility SNPs in HLA region and evidence of interaction between rs6457617 in HLA-DQB1 and HLA-DRB1*04 locus on Tunisian rheumatoid arthritis.
Journal of genetics - 1 Dec 2017
Achour Yosser, Ben Hamad Mariem, Chaabane Souhir, Rebai Ahmed, Marzouk Sameh, Mahfoudh Nadia, Bahloul Zouhir, Keskes Leila, Maalej Abdellatif
Abstract excerpt
Previous genomewide association studies (GWAS) and meta-analyses have enumerated several genes/loci in major histocompatibility complex region, which are consistently associated with rheumatoid arthritis (RA) in different ethnic populations. Given the genetic heterogeneity of the disease, it is necessary to replicate these susceptibility loci in other populations. In this case, we investigate the analysis of two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
