Article
An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.
PLoS genetics - 1 Sept 2014
Williams Evan G, Mouchiroud Laurent, Frochaux Michael, Pandey Ashutosh, Andreux Pénélope A, Deplancke Bart, Auwerx Johan
Abstract excerpt
The BXD genetic reference population is a recombinant inbred panel descended from crosses between the C57BL/6 (B6) and DBA/2 (D2) strains of mice, which segregate for about 5 million sequence variants. Recently, some of these variants have been established with effects on general metabolic phenotypes such as glucose response and bone strength. Here we phenotype 43 BXD strains and observe they have large variation...
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