Article
Genetic architecture of voluntary exercise in an advanced intercross line of mice.
Physiological genomics - 7 Jul 2010
Kelly Scott A, Nehrenberg Derrick L, Peirce Jeremy L, Hua Kunjie, Steffy Brian M, Wiltshire Tim, Pardo-Manuel de Villena Fernando, Garland Theodore, Pomp Daniel
Abstract excerpt
Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects of quantitative trait loci (QTL) controlling genetic predisposition for exercise-related traits, utilizing a large advanced intercross line (AIL) of mice. This AIL (G(4)) population originated from a reciprocal...
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