Article
Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Apr 2010
Aarnio Vuokko, Storvik Markus, Lehtonen Marko, Asikainen Suvi, Reisner Kaja, Callaway James, Rudgalvyte Martina, Lakso Merja, Wong Garry
Abstract excerpt
The aryl hydrocarbon receptor (AHR) is a eukaryotic transcription factor that plays an essential role in neuronal, immune, vascular, hepatic and hematopoietic development. In mammals, AHR induces metabolism-associated genes in response to xenobiotics. AHR is evolutionarily conserved, and the C. elegans AHR ortholog likely shares many physiologic functions with the mammalian version. While the role of AHR in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
