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An improved and validated RNA HLA class I SBT approach for obtaining full length coding sequences.

Tissue antigens - 1 Nov 2014

Gerritsen K E H, Olieslagers T I, Groeneweg M, Voorter C E M, Tilanus M G J

Abstract excerpt

The functional relevance of human leukocyte antigen (HLA) class I allele polymorphism beyond exons 2 and 3 is difficult to address because more than 70% of the HLA class I alleles are defined by exons 2 and 3 sequences only. For routine application on clinical samples we improved and validated the HLA sequence-based typing (SBT) approach based on RNA templates, using either a single locus-specific or two...

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PMID: 25251784
DOI: 10.1111/tan.12436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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