Article
Genome-wide analysis of hepatic lipid content in extreme obesity.
Acta diabetologica - 1 Apr 2015
DiStefano Johanna K, Kingsley Christopher, Craig Wood G, Chu Xin, Argyropoulos George, Still Christopher D, Doné Stefania Cotta, Legendre Christophe, Tembe Waibhav, Gerhard Glenn S
Abstract excerpt
AIMS: Individuals with type 2 diabetes have an increased risk of developing non-alcoholic fatty liver disease (NAFLD), and NAFLD patients are also at greater risk for developing type 2 diabetes. Although the relationship between type 2 diabetes and NAFLD is highly interconnected, the pathogenic mechanisms linking the two diseases are poorly understood. The goal of this study was to identify genetic determinants...
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