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Article

Clinical and Genetic Predictors of Non-Alcoholic Steatotic Liver Disease and Fibrosis in Lean Individuals.

Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2025

Sato-Espinoza Karina, Vierkant Robert A, Chotiprasidhi Perapa, Vairo Filippo Pinto E, Tian Shulan, Ma Jun, O'Brien Daniel, Lazaridis Konstantinos N, Dlugosch Carola, Scheider Carolin, Allen Alina M, Wangensteen Kirk J

Abstract excerpt

BACKGROUND & AIMS: Steatotic liver disease (SLD) is characterised by liver fat accumulation exceeding 5%. Lean body weight (BMI ≤ 25 kg/m2) with non-alcoholic SLD is a rare phenotype, and the balance of risks related to metabolic conditions or genetic predisposition, or the risk of progressive liver disease, is not known. This study evaluates clinical and genetic predictors of non-alcoholic SLD and advanced liver...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40944478
DOI: 10.1111/liv.70300
PMCID: PMC13215060

Genes

GCKR
PNPLA3

Provenance

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