Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuropilin-1+ regulatory T cells promote skin allograft survival and modulate effector CD4+ T cells phenotypic signature.

Immunology and cell biology - 1 Feb 2015

Campos-Mora Mauricio, Morales Rodrigo A, Pérez Francisco, Gajardo Tania, Campos Javier, Catalan Diego, Aguillón Juan Carlos, Pino-Lagos Karina

Abstract excerpt

During allograft rejection, several immune cell types, including dendritic cells, CD4(+) and CD8(+) T cells among others, recirculate between the graft and the nearest draining lymph node, resulting in immunity against the 'foreign' tissue. Regulatory CD4(+) T cells are critical for controlling the magnitude of the immune response and may act to promote or maintain tolerance. They are characterized by the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allografts
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Survival

Share to Mice, Inbred BALB C

Share to Nerve Tissue Proteins

Share to Neuropilin-1

Share to Skin Transplantation

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 25245111
DOI: 10.1038/icb.2014.77

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuropilin-1+ regulatory T cells promote skin allograft survival and modulate effector CD4+ T cells phenotypic signature.PMID 25245111Read ↗

Neuropilin-1 expression is induced on tolerant self-reactive CD8+ T cells but is dispensable for the tolerant phenotype.Semantic proximity Read ↗

Neuropilin-2 functions as a co-inhibitory receptor to regulate antigen-induced inflammation and allograft rejectionSemantic proximity Read ↗

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responsesSemantic proximity Read ↗

Netrin-1 prolongs skin graft survival by inducing the transformation of mesenchymal stem cells from pro-rejection to immune-tolerant phenotype.Semantic proximity Read ↗

Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directions.Semantic proximity Read ↗

Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesisSemantic proximity Read ↗

TGF-β-induced Tregs release extracellular vesicles that modulate CD4+ T-cell proliferation and phenotype in a Nrp1-dependent manner.Semantic proximity Read ↗

Type 1 T-regulatory cells: their role in the control of immune responses.Semantic proximity Read ↗

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2 responding CD4 <sup>+</sup> T cellsSemantic proximity Read ↗

Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation.Semantic proximity Read ↗

Expression profiling of murine double-negative regulatory T cells suggest mechanisms for prolonged cardiac allograft survival.Semantic proximity Read ↗

CD8+ regulatory T cells in solid organ transplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.