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Article

Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directions.

Journal of molecular cell biology - 1 Feb 2012

Juvet Stephen C, Zhang Li

Abstract excerpt

T lymphocytes bearing the αβ T cell receptor (TCR) but lacking CD4, CD8, and markers of natural killer (NK) cell differentiation are known as 'double-negative' (DN) T cells and have been described in both humans and rodent models. We and others have shown that DN T cells can act as regulatory T c...

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Identifiers

PMID: 22294241
DOI: 10.1093/jmcb/mjr043
PMCID: PMC3269300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22294241-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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