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Article

NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity.

Cell reports - 25 Sept 2014

Ehlers Melissa L, Celona Barbara, Black Brian L

Abstract excerpt

Skeletal muscle comprises a heterogeneous population of fibers with important physiological differences. Fast fibers are glycolytic and fatigue rapidly. Slow fibers utilize oxidative metabolism and are fatigue resistant. Muscle diseases such as sarcopenia and atrophy selectively affect fast fibers, but the molecular mechanisms regulating fiber type-specific gene expression remain incompletely understood. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25242327
DOI: 10.1016/j.celrep.2014.08.035
PMCID: PMC4180018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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