Article
A gene variant in CERS2 is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND.
PloS one - 1 Jan 2014
Shiffman Dov, Pare Guillaume, Oberbauer Rainer, Louie Judy Z, Rowland Charles M, Devlin James J, Mann Johannes F, McQueen Matthew J
Abstract excerpt
Although albuminuria and subsequent advanced stage chronic kidney disease are common among patients with diabetes, the rate of increase in albuminuria varies among patients. Since genetic variants associated with estimated glomerular filtration rate (eGFR) were identified in cross sectional studies, we asked whether these variants were also associated with rate of increase in albuminuria among patients with...
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