Article
Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study.
BMC medical genetics - 19 Jan 2011
Hsu Charles C, Kao Wenhong L, Steffes Michael W, Gambir Tejal, Brancati Frederick L, Heilig Charles W, Shuldiner Alan R, Boerwinkle Eric A, Coresh Josef
Abstract excerpt
BACKGROUND: Evidence suggests glucose transporter-1 (GLUT1) genetic variation affects diabetic nephropathy and albuminuria. Our aim was to evaluate associations with albuminuria of six GLUT1 single nucleotide polymorphisms(SNPs), particularly XbaI and the previously associated Enhancer-2 (Enh2) SNP. METHODS: A two-stage case-control study was nested in a prospective cohort study of 2156 African Americans and 8122...
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