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The Superior Adherence Phenotype of E. coli O104:H4 is Directly Mediated by the Aggregative Adherence Fimbriae Type I.

Virulence - 1 Dec 2021

Schiller Philipp, Knödler Michael, Berger Petya, Greune Lilo, Fruth Angelika, Mellmann Alexander, Dersch Petra, Berger Michael, Dobrindt Ulrich

Abstract excerpt

Whereas the O104:H4 enterohemorrhagic Escherichia coli (EHEC) outbreak strain from 2011 expresses aggregative adherence fimbriae of subtype I (AAF/I), its close relative, the O104:H4 enteroaggregative Escherichia coli (EAEC) strain 55989, encodes AAF of subtype III. Tight adherence mediated by AAF/I in combination with Shiga toxin 2 production has been suggested to result in the outbreak strain's exceptional...

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Identifiers

PMID: 33356871
DOI: 10.1080/21505594.2020.1868841
PMCID: PMC7834096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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