Article
Crystal structure of the transport unit of the autotransporter adhesin involved in diffuse adherence from Escherichia coli.
Journal of structural biology - 1 Jul 2014
Gawarzewski Iris, DiMaio Frank, Winterer Elisa, Tschapek Britta, Smits Sander H J, Jose Joachim, Schmitt Lutz
Abstract excerpt
Several serious gastrointestinal diseases, which are widespread all over the world, are caused by enteropathogenic Escherichia coli. The monomeric autotransporter AIDA-I (adhesin involved in diffuse adherence) represents an important virulence factor of these strains and is involved in adhesion, biofilm formation, aggregation and invasion into host cells. Here, we present the crystal structure of the transport...
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