Article
Evolutionary and functional relationships of colonization factor antigen i and other class 5 adhesive fimbriae of enterotoxigenic Escherichia coli.
Infection and immunity - 1 Dec 2004
Anantha Ravi P, McVeigh Annette L, Lee Lanfong H, Agnew Mary K, Cassels Frederick J, Scott Daniel A, Whittam Thomas S, Savarino Stephen J
Abstract excerpt
Colonization factor antigen I (CFA/I) is the archetype of eight genetically related fimbriae of enterotoxigenic Escherichia coli (ETEC) designated class 5 fimbriae. Assembled by the alternate chaperone pathway, these organelles comprise a rigid stalk of polymerized major subunits and an apparently tip-localized minor adhesive subunit. We examined the evolutionary relationships of class 5-specific structural...
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