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Article

Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cells.

Cell biology international - 1 Mar 2015

Sharma Shaveta, Kaul Deepak, Arora Mansi, Malik Deepti

Abstract excerpt

Since apoptosis presents a natural defense in cancer development, the anti-apoptotic factor AATF/Che-1 has emerged as a crucial 'Epigenomic-Switch'. We have tried to understand the double-edged nature of AATF, showing for the first time the conspicuous existence of an aberrant AATF/Che-1 transcriptome encoding for 23 kDa mutant AATF protein, which evolves its unique interactome within human cancer cells derived...

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Identifiers

PMID: 25231211
DOI: 10.1002/cbin.10379

Genes

AATF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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