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Article

Hodgkin disease therapy induced second malignancy susceptibility 6q21 functional variants in roma and hungarian population samples.

Pathology oncology research : POR - 1 Jul 2014

Varszegi Dalma, Duga Balazs, Melegh Bela I, Sumegi Katalin, Kisfali Peter, Maasz Anita, Melegh Bela

Abstract excerpt

Patients treated successfully for pediatric Hodgkin's lymphoma are known to develop secondary malignancies; care is already taken in treatment to prevent this adverse effect. Recent GWAS study identified rs4946728 and rs1040411 noncoding SNPs located between PRDM1 and ATG1 genes on chromosome 6q21 as risk factors for secondary malignancies in patients formerly treated with radiotherapy for pediatric Hodgkin...

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Source

Identifiers

PMID: 24306881
DOI: 10.1007/s12253-013-9724-z

Genes

PRDM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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