Major histocompatibility complex class I and class II alleles may confer susceptibility to or protection against morphea: findings from the Morphea in Adults and Children cohort.

Abstract excerpt

OBJECTIVE: To determine the HLA class I and class II alleles of the human major histocompatibility complex showing an association with morphea (localized scleroderma) in the Morphea in Adults and Children (MAC) cohort, using a nested case-control association study. METHODS: Patients with morphea were identified from the MAC cohort, and matched controls were obtained from the National Institutes of Health/National...

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