Article
The molecular pathogenesis of morphoea: from genetics to future treatment targets.
The British journal of dermatology - 1 Jul 2017
Saracino A M, Denton C P, Orteu C H
Abstract excerpt
A number of immunoinflammatory and profibrotic mechanisms are recognized in the pathogenesis of broad sclerotic skin processes and, more specifically, morphoea. However, the precise aetiopathogenesis is complex and remains unclear. Morphoea is clinically heterogeneous, with variable anatomical patterning, depth of tissue involvement and sclerotic, inflammatory, atrophic and dyspigmented morphology. Underlying...
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