Article
Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians.
Arthritis and rheumatism - 1 Dec 2006
Mamyrova Gulnara, O'Hanlon Terrance P, Monroe Jason B, Carrick Danielle Mercatante, Malley James D, Adams Sharon, Reed Ann M, Shamim Ejaz A, James-Newton Laura, Miller Frederick W, Rider Lisa G
Abstract excerpt
OBJECTIVE: To define the relative importance (RI) of class II major histocompatibility complex (MHC) alleles and peptide binding motifs as risk or protective factors for juvenile dermatomyositis (DM), and to compare these with HLA associations in adult DM. METHODS: DRB1 and DQA1 typing was performed in 142 Caucasian patients with juvenile DM, and the results were compared with HLA typing data from 193 patients...
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