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Article

SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter.

Virology - 1 Nov 2014

Smith Jennifer A, Haberstroh Friederike S, White Elizabeth A, Livingston David M, DeCaprio James A, Howley Peter M

Abstract excerpt

An important step in the malignant progression of HPV-associated lesions is the dysregulation of expression of the viral E6 and E7 oncogenes. This is often achieved through the loss of expression of E2, which represses the HPV LCR promoter and E6/E7 expression. Our previous studies confirmed a ro...

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Identifiers

PMID: 25222147
DOI: 10.1016/j.virol.2014.08.022
PMCID: PMC4252969

Genes

TRRAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25222147-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter.PMID 25222147Read ↗

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