Article
Filter Paper-based Nucleic Acid Storage in High-throughput Solid Tumor Genotyping.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000
Stachler Matthew, Jia Yonghui, Sharaf Nematullah, Wade Jacqueline, Longtine Janina, Garcia Elizabeth, Sholl Lynette M
Abstract excerpt
Molecular testing of tumors from formalin-fixed paraffin-embedded (FFPE) tissue blocks is central to clinical practice; however, it requires histology support and increases test turnaround time. Prospective fresh frozen tissue collection requires special handling, additional storage space, and may not be feasible for small specimens. Filter paper-based collection of tumor DNA reduces the need for histology...
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