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Article

KRAS detection in colonic tumors by DNA extraction from FTA paper: the molecular touch-prep.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2011

Petras Melissa L, Lefferts Joel A, Ward Brian P, Suriawinata Arief A, Tsongalis Gregory J

Abstract excerpt

DNA isolated from formalin-fixed paraffin-embedded (FFPE) tissue is usually more degraded and contains more polymerase chain reaction (PCR) inhibitors than DNA isolated from nonfixed tissue. In addition, the tumor size and cellular heterogeneity found in tissue sections can often impact testing for molecular biomarkers. As a potential remedy to this situation, we evaluated the use of Whatman FTA paper cards for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22089345
DOI: 10.1097/PDM.0b013e318211d554

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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