Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.

doi:10.1176/appi.ajp.2009.09070932

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Article

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.

The American journal of psychiatry - 1 May 2010

Uher Rudolf, Perroud Nader, Ng Mandy Y M, Hauser Joanna, Henigsberg Neven, Maier Wolfgang, Mors Ole, Placentino Anna, Rietschel Marcella, Souery Daniel, Zagar Tina, Czerski Piotr M, Jerman Borut, Larsen Erik Roj, Schulze Thomas G, Zobel Astrid, Cohen-Woods Sarah, Pirlo Katrina, Butler Amy W, Muglia Pierandrea, Barnes Michael R, Lathrop Mark, Farmer Anne, Breen Gerome, Aitchison Katherine J, Craig Ian, Lewis Cathryn M, McGuffin Peter

Abstract excerpt

OBJECTIVE: The purpose of this study was to identify genetic variants underlying the considerable individual differences in response to antidepressant treatment. The authors performed a genome-wide association analysis of improvement of depression severity with two antidepressant drugs. METHOD: High-quality Illumina Human610-quad chip genotyping data were available for 706 unrelated participants of European...

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PMID: 20360315
DOI: 10.1176/appi.ajp.2009.09070932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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