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Article

Genetic Role of BDNF Val66Met and 5-HTTLPR Polymorphisms on Depressive Disorder

1 Jan 2014

Abstract excerpt

OBJECTIVE: We investigated possible association between depressive disorders and BDNF Val66Met and 5-HTTLPR. Brain derived neurotrophic factor (BDNF) gene and serotonin transporter (SLC6A4) gene are promising candidate genes for depressive disorders. It has been suggested that BDNF promotes the survival and differentiation of serotonergic neurons and that serotonergic transmission exerts powerful control over...

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PMID: 24843376
DOI: 10.4306/pi.2014.11.2.192

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