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Article

Association of the C(-1019)G 5-HT1A promoter polymorphism with exposure to stressors preceding hospitalization for bipolar depression.

Journal of affective disorders - 1 Jul 2011

Benedetti Francesco, Radaelli Daniele, Poletti Sara, Locatelli Clara, Dallaspezia Sara, Lorenzi Cristina, Pirovano Adele, Colombo Cristina, Smeraldi Enrico

Abstract excerpt

RATIONALE: In animals, a higher density of 5-HT1A receptors has been associated with increased behavioral despair after stress. In humans, the G variant of the C(-1019)G 5-HT1A receptor promoter gene polymorphism (rs6295) has been associated with higher expression of 5-HT1A receptors, increased depression, and lower stress preceding completed suicide. OBJECTIVES: We studied the association of rs6295 with the...

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Source

Identifiers

PMID: 21397953
DOI: 10.1016/j.jad.2011.02.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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