Article
Long-term follow-up of cytogenetically normal CEBPA-mutated AML.
Journal of hematology & oncology - 10 Sept 2014
Pastore Friederike, Kling Daniela, Hoster Eva, Dufour Annika, Konstandin Nikola P, Schneider Stephanie, Sauerland Maria C, Berdel Wolfgang E, Buechner Thomas, Woermann Bernhard, Braess Jan, Hiddemann Wolfgang, Spiekermann Karsten
Abstract excerpt
BACKGROUND: The aim of this study was to analyze the long-term survival of AML patients with CEBPA mutations. PATIENTS AND METHODS: We investigated 88 AML patients with a median age of 61 years and (1) cytogenetically normal AML (CN-AML), (2) monoallelic (moCEBPA) or biallelic (biCEBPA) CEBPA mutation, and (3) intensive induction treatment. 60/88 patients have been described previously with a shorter follow-up....
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