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DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers

31 May 2020

Abstract excerpt

Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also reveals alterations in its methylation profile. The intrinsic ability of HPV oncoproteins E6 and E7 to interfere with DNA methyltransferase activity contributes to these methylation changes. There are many genes that have been reported to be...

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PMID: 32486347
DOI: 10.3390/cells9061359

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