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Article

Genome-wide association studies: getting to pathogenesis, the role of inflammation/complement in age-related macular degeneration.

Cold Spring Harbor perspectives in medicine - 11 Sept 2014

Cooke Bailey Jessica N, Pericak-Vance Margaret A, Haines Jonathan L

Abstract excerpt

Age-related macular degeneration (AMD) is a chronic, degenerative, and significant cause of visual impairment and blindness in the elderly. Genetic and epidemiological studies have confirmed that AMD has a strong genetic component, which has encouraged the application of increasingly sophisticated genetic techniques to uncover the important underlying genetic variants. Although various genes and pathways have...

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Identifiers

PMID: 25213188
DOI: 10.1101/cshperspect.a017186
PMCID: PMC4292090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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