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Complement, Age-Related Macular Degeneration and a Vision of the Future

1 Mar 2010

Abstract excerpt

Age-related macular degeneration (AMD) is one of the most well-characterized late-onset, complex trait diseases. Remarkable advances in our understanding of the genetic and biological foundations of this disease were derived from a recent convergence of scientific and clinical data. Importantly, the more recent identification of AMD-associated variations in a number of complement pathway genes has provided strong...

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PMID: 20212207
DOI: 10.1001/archophthalmol.2010.18

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