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Article

Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation.

PloS one - 1 Jan 2014

Carty Shannon A, Koretzky Gary A, Jordan Martha S

Abstract excerpt

Interleukin (IL)-4 is a cytokine classically associated with CD4(+) T helper type 2 differentiation, but has been recently shown to also be required for the development of CD8(+) innate-like lymphocytes. CD8(+) innate-like lymphocytes are non-conventional lymphocytes that exhibit characteristics typically associated with memory CD8(+) T cells, including expression of the T-box transcription factor Eomesodermin...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins c-akt

Share to Receptors, Antigen, T-Cell

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Source

Open in PubMed Open full text

Identifiers

PMID: 25207963
DOI: 10.1371/journal.pone.0106659
PMCID: PMC4160212

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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