Article
Global microRNA expression is essential for murine mast cell development in vivo.
Experimental hematology - 1 Oct 2014
Oh Sun Young, Brandal Stephanie, Kapur Reuben, Zhu Zhou, Takemoto Clifford M
Abstract excerpt
MicroRNAs (miRNAs) are small, noncoding RNAs that have been shown to play a critical role in normal physiology and disease, such as hematopoietic development and cancer. However, their role in mast-cell function and development is poorly understood. The major objective of this study was to determine how global miRNA expression affects mast-cell physiology. The RNase III endonuclease, Dicer, is required for the...
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