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Gene expression variations: potentialities of master regulator polymorphisms in colorectal cancer risk.

Mutagenesis - 1 Mar 2012

Pardini Barbara, Naccarati Alessio, Vodicka Pavel, Kumar Rajiv

Abstract excerpt

Colorectal cancer (CRC) is one of the most common cancers worldwide with a peak of incidence in industrialised countries. It is a complex disease related to environmental and genetic risk factors. Low-penetrance genetic variations contribute significantly to sporadic and familial form of CRC. Genome-wide association studies (GWAS) have uncovered numerous robust associations between common variants and CRC risk;...

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Colorectal Neoplasms
Gene Expression Regulation, Neoplastic
Genome, Human
Genome-Wide Association Study
Penetrance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Quantitative Trait Loci

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PMID: 22294763
DOI: 10.1093/mutage/ger057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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