Article
Gene expression variations: potentialities of master regulator polymorphisms in colorectal cancer risk.
Mutagenesis - 1 Mar 2012
Pardini Barbara, Naccarati Alessio, Vodicka Pavel, Kumar Rajiv
Abstract excerpt
Colorectal cancer (CRC) is one of the most common cancers worldwide with a peak of incidence in industrialised countries. It is a complex disease related to environmental and genetic risk factors. Low-penetrance genetic variations contribute significantly to sporadic and familial form of CRC. Genome-wide association studies (GWAS) have uncovered numerous robust associations between common variants and CRC risk;...
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