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Article

Impaired vitamin D activation and association with CYP24A1 haplotypes in differentiated thyroid carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Jul 2012

Penna-Martinez Marissa, Ramos-Lopez Elizabeth, Stern Julienne, Kahles Heinrich, Hinsch Nora, Hansmann Martin-Leo, Selkinski Ivan, Grünwald Frank, Vorländer Christian, Bechstein Wolf O, Zeuzem Stefan, Holzer Katharina, Badenhoop Klaus

Abstract excerpt

BACKGROUND: Common polymorphisms of the vitamin D receptor gene have been reported to affect the risk of breast, colon, prostate, and differentiated thyroid cancer (DTC), but polymorphisms within the genes of vitamin D metabolizing enzymes have not been studied in DTC. The aim of the present study was to investigate the genes for vitamin D enzymes in patients with DTC and healthy controls (HC) as well as the...

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Identifiers

PMID: 22690899
DOI: 10.1089/thy.2011.0330
PMCID: PMC3387756

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