Article
Vitamin D receptor polymorphisms in differentiated thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Jun 2009
Penna-Martinez Marissa, Ramos-Lopez Elizabeth, Stern Julienne, Hinsch Nora, Hansmann Martin-Leo, Selkinski Ivan, Grünwald Frank, Vorländer Christian, Wahl Robert A, Bechstein Wolf O, Zeuzem Stefan, Holzer Katharina, Badenhoop Klaus
Abstract excerpt
BACKGROUND: Vitamin D receptor (VDR) expression has been shown to be upregulated in several tumors and is supposed to represent an important endogenous response to tumor progression. To investigate the role of the VDR gene and its influence on 25(OH)D(3) and 1,25(OH)(2)D(3) plasma levels in thyroid carcinoma, we analyzed four VDR polymorphisms in patients and healthy controls (HC). METHODS: Patients with thyroid...
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