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Identification of Genomic Binding Sites for Candida glabrata Pdr1 Transcription Factor in Wild-Type and ρ <sup>0</sup> Cells

9 Sept 2014

Abstract excerpt

The fungal pathogen Candida glabrata is an emerging cause of candidiasis in part owing to its robust ability to acquire tolerance to the major clinical antifungal drug fluconazole. Similar to the related species Candida albicans, C. glabrata most typically gains azole tolerance via transcriptional induction of a suite of resistance genes, including a locus encoding an ABCG-type ATP-binding cassette (ABC)...

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PMID: 25199772
DOI: 10.1128/aac.03921-14

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Identification of Genomic Binding Sites for Candida glabrata Pdr1 Transcription Factor in Wild-Type and ρ <sup>0</sup> CellsPMID 25199772Read ↗

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Overlapping coactivator function is required for transcriptional activation by the <i>Candida glabrata</i> Pdr1 transcription factorSemantic proximity Read ↗

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Calcineurin is required for <i>Candida glabrata</i> Pdr1 transcriptional activationSemantic proximity Read ↗

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