Article
Lack of correlation between ERCC1 (C8092A) single nucleotide polymorphism and efficacy/toxicity of platinum based chemotherapy in Chinese patients with advanced non-small cell lung cancer.
Advances in medical sciences - 1 Jan 2011
KimCurran V, Zhou C, Schmid-Bindert G, Shengxiang Ren, Zhou S, Zhang L, Zhang J
Abstract excerpt
PURPOSE: We investigated whether single nucleotide polymorphism of excision repair cross-complementation group 1 C8092A affected the clinical outcomes and toxicity in advanced stage non-small cell lung cancer patients receiving first line platinum based chemotherapy. MATERIAL/METHODS: A total of 300 chemotherapy treated patients were examined for C8092A genotypes in peripheral blood samples. RESULTS: Overall...
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